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Updated: Aug 17, 2026

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ACRP ACRP-CP Exam Overview:

Certification Vendor:ACRP (Association of Clinical Research Professionals)
Exam Name:ACRP Certified Professional (ACRP-CP) Certification Exam
Exam Number:ACRP-CP
Available Languages:English
Exam Duration:180 minutes
Exam Format:Multiple choice, Computer-based testing
Real Exam Qty:Approximately 130
Related Certifications:ACRP Certified Clinical Research Coordinator (CCRC)
ACRP Certified Clinical Research Associate (CCRA)
Recommended Training:ACRP Official Training & Education
Exam Registration:Pearson VUE Registration Portal
ACRP Certification Page
Sample Questions:ACRP ACRP-CP Sample Questions
Exam Way:Computer-based exam delivered via test centers and/or remote proctoring through authorized testing provider
Pre Condition:Professional experience in clinical research is typically required (commonly around 2–3+ years depending on eligibility pathway); eligibility requirements vary by pathway on the official ACRP certification policy.
Official Syllabus URL:https://www.acrpnet.org/

ACRP ACRP-CP Exam Syllabus Topics:

SectionObjectives
Regulatory Compliance- Regulatory documentation and submissions
- Audit and inspection readiness
Data and Quality Management- Quality assurance and quality control
- Clinical data management principles
Participant Safety and Protection- Safety reporting and adverse events
- Informed consent process
Clinical Research Foundations- Ethical conduct in clinical trials
- Good Clinical Practice (GCP) principles
Study Operations- Study planning and initiation
- Study conduct and oversight

ACRP Certified Professional Sample Questions:

1. A trial subject was involved in a traffic accident. The emergency room (ER) doctor notifies the investigator that he wants to give the subject a blood transfusion. Blood transfusion is one of the prohibited treatments in the trial. How should the investigator respond?

A) Ask the ER doctor not to transfuse blood and consider another treatment compliant with the protocol.
B) Advise the ER doctor to transfuse the blood, and the PI should report this incident to the sponsor.
C) Report this incident immediately to the sponsor and leave the treatment decision to them.
D) Advise the ER doctor to transfuse blood, and the PI should withdraw the subject from the trial.


2. A representative from a regulatory authority shows up unannounced at a research site. After confirming their credentials, the representative requested to view the entire records, including identifiable information, from study XYZ that was closed out. Which of the following should the site personnel do next?

A) Redact subject identification for privacy protection.
B) Deny the request until the sponsor approves.
C) Allow access to the entire records.
D) Consult with the IRB/IEC first.


3. Who is responsible to ensure training for key staff members unable to attend the site initiation visit?

A) Monitor
B) Coordinator
C) Investigator
D) Sponsor


4. The site submitted all start-up documents for a study to the sponsor and the IRB/IEC. The site also has subjects identified for screening. What should happen FIRST?

A) Schedule a site initiation visit
B) Ship/receive IP
C) Obtain IRB/IEC approval
D) Verify subject eligibility


5. After enrolling and treating a few subjects on an investigator-initiated trial, the PI would like to include a subject diary for each trial subject to capture their activities and experiences on the trial regimen. After the PI has generated a diary, what should the PI do next?

A) Submit the diary to the regulatory authority for approval.
B) No approval is necessary: give the diary to each subject.
C) Submit the diary to the IRB/IEC for approval.
D) Submit the diary to the sponsor for approval.


Solutions:

Question # 1
Answer: B
Question # 2
Answer: C
Question # 3
Answer: C
Question # 4
Answer: C
Question # 5
Answer: C

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