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Updated: May 31, 2026
No. of Questions: 204 Questions & Answers with Testing Engine
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American Society of Microbiology ABMM Sample Questions:
1. A patient develops a localized skin infection after being bitten by a tick. The infection is characterized by a slowly expanding erythematous rash with central clearing (erythema migrans). The MOST likely causative agent is:
A) Borrelia burgdorferi
B) Ehrlichia chaffeensis
C) Anaplasma phagocytophilum
D) Rickettsia rickettsii
2. A research team is investigating the mechanisms of antifungal resistance in Candida albicans. They identify a strain that exhibits resistance to azole antifungal agents. Further analysis reveals overexpression of a specific ATP-binding cassette (ABC) transporter protein in the resistant strain. This mechanism of resistance involves:
A) Alteration of the fungal ergosterol biosynthesis pathway, the target of azoles.
B) Increased degradation of the azole antifungal agent within the fungal cell.
C) Modification of the fungal cell wall, preventing azole penetration.
D) Active efflux of the azole antifungal agent out of the fungal cell.
3. A microbiology laboratory receives a corneal scraping from a patient with keratitis. Microscopic examination with calcofluor white stain reveals the presence of septate hyphae and conidiophores with a foot cell and phialides. The MOST likely genus is:
A) Mucor
B) Candida
C) Aspergillus
D) Rhizopus
4. A patient with HIV infection and a low CD4+ T-cell count presents with fever, weight loss, and cough. Chest X-ray shows diffuse interstitial infiltrates. Sputum induction reveals oval yeast cells with narrow-based budding. The MOST likely diagnosis is:
A) Tuberculosis
B) Pneumocystis pneumonia
C) Histoplasmosis
D) Cryptococcosis
5. A microbiology laboratory receives a wound swab from a patient with a chronic, non-healing ulcer. Culture yields a Gram-positive, branching filamentous bacterium that is partially acid-fast. The MOST likely genus is:
A) Nocardia
B) Mycobacterium
C) Streptomyces
D) Actinomyces
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: D | Question # 3 Answer: C | Question # 4 Answer: C | Question # 5 Answer: A |
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