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Updated: Sep 16, 2026

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American Society of Microbiology ABMM Exam Overview:

Certification Vendor:American Society for Microbiology (ASM) - American College of Microbiology
Exam Name:ABMM Certification Examination (American Board of Medical Microbiology)
Exam Number:ABMM
Related Certifications:American Board of Medical Laboratory Immunology (ABMLI)
Available Languages:English
Exam Format:Written Examination, Oral Examination (may be required depending on candidate pathway), Credential/Document Review
Sample Questions:American Society of Microbiology ABMM Sample Questions
Exam Way:In-person examination (location varies; administered under ASM certification program policies).
Pre Condition:Doctoral degree (PhD, MD, or equivalent) in microbiology or a related biomedical field, plus relevant clinical microbiology training/experience.

American Society of Microbiology ABMM Exam Syllabus Topics:

SectionObjectives
Topic 1: Laboratory Management & Quality Systems- Regulatory compliance
  • 1. Clinical laboratory regulations and accreditation standards
    • 2. Safety and biosafety requirements
      - Quality assurance and quality control
      • 1. Proficiency testing and validation
        • 2. Laboratory quality systems design
          Topic 2: Infectious Disease Principles- Pathogenesis
          • 1. Host-pathogen interactions
            • 2. Mechanisms of microbial infection
              - Epidemiology
              • 1. Transmission and outbreak investigation
                • 2. Public health microbiology
                  Topic 3: Clinical Microbiology- Virology
                  • 1. Diagnostic virology methods
                    • 2. Clinical viral pathogens
                      - Parasitology
                      • 1. Diagnostic techniques in parasitology
                        • 2. Human parasitic infections
                          - Bacteriology
                          • 1. Identification and classification of bacterial pathogens
                            • 2. Antimicrobial susceptibility testing principles
                              - Mycology
                              • 1. Laboratory identification of fungi
                                • 2. Medical fungal infections
                                  Topic 4: Laboratory Operations- Diagnostic workflow
                                  • 1. Test selection and interpretation
                                    • 2. Specimen handling and processing
                                      - Instrumentation and methodologies
                                      • 1. Molecular diagnostic techniques
                                        • 2. Automated microbiology systems

                                          American Society of Microbiology ABMM Sample Questions:

                                          Question #1

                                          A patient develops a localized skin infection after being bitten by a tick. The infection is characterized by a slowly expanding erythematous rash with central clearing (erythema migrans). The MOST likely causative agent is:

                                          • A. Borrelia burgdorferi
                                          • B. Ehrlichia chaffeensis
                                          • C. Anaplasma phagocytophilum
                                          • D. Rickettsia rickettsii
                                          Reveal Solution  Discussion  0

                                          Correct Answer: A  🗳️

                                          Question #2

                                          A research team is investigating the mechanisms of antifungal resistance in Candida albicans. They identify a strain that exhibits resistance to azole antifungal agents. Further analysis reveals overexpression of a specific ATP-binding cassette (ABC) transporter protein in the resistant strain. This mechanism of resistance involves:

                                          • A. Alteration of the fungal ergosterol biosynthesis pathway, the target of azoles.
                                          • B. Increased degradation of the azole antifungal agent within the fungal cell.
                                          • C. Modification of the fungal cell wall, preventing azole penetration.
                                          • D. Active efflux of the azole antifungal agent out of the fungal cell.
                                          Reveal Solution  Discussion  0

                                          Correct Answer: D  🗳️

                                          Question #3

                                          A microbiology laboratory receives a corneal scraping from a patient with keratitis. Microscopic examination with calcofluor white stain reveals the presence of septate hyphae and conidiophores with a foot cell and phialides. The MOST likely genus is:

                                          • A. Mucor
                                          • B. Candida
                                          • C. Aspergillus
                                          • D. Rhizopus
                                          Reveal Solution  Discussion  0

                                          Correct Answer: C  🗳️

                                          Question #4

                                          A patient with HIV infection and a low CD4+ T-cell count presents with fever, weight loss, and cough. Chest X-ray shows diffuse interstitial infiltrates. Sputum induction reveals oval yeast cells with narrow-based budding. The MOST likely diagnosis is:

                                          • A. Tuberculosis
                                          • B. Pneumocystis pneumonia
                                          • C. Histoplasmosis
                                          • D. Cryptococcosis
                                          Reveal Solution  Discussion  0

                                          Correct Answer: C  🗳️

                                          Question #5

                                          A microbiology laboratory receives a wound swab from a patient with a chronic, non-healing ulcer. Culture yields a Gram-positive, branching filamentous bacterium that is partially acid-fast. The MOST likely genus is:

                                          • A. Nocardia
                                          • B. Mycobacterium
                                          • C. Streptomyces
                                          • D. Actinomyces
                                          Reveal Solution  Discussion  0

                                          Correct Answer: A  🗳️

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